Rediff.com takes a look at a few such players, whose lone major title win came at the Paris Masters.
India's tennis ace Sania Mirza rose to a career-best ranking of World No 6 in doubles in the new tennis rankings released on Monday.
Andy Murray will draw on the experience of being a grand slam champion and Ernests Gulbis will rely on his "unhealthy diet full of ketchup" as they attempt to prevent a Rafael Nadal-Novak Djokovic final at the French Open.
Clay has long been Maria Sharapova's least favoured surface, but the Russian, who takes on Eugenie Bouchard on Thursday, is on the brink of reaching her third successive French Open final, a feat she has never achieved in the other Grand Slams.
Germany's Andrea Petkovic reached her first Grand Slam semi-final on Wednesday, thrashing 10th seed Sara Errani 6-2, 6-2 after a lengthy rain delay at the French Open.
Images from Day 7 of the 2021 French Open at Roland Garros in Paris on Saturday.
Defending champion Rafa Nadal dismantled unseeded Serbian Dusan Lajovic 6-1, 6-2, 6-1 on Monday to set up a French Open quarter-final clash with fellow Spaniard David Ferrer in a repeat of last year's final.
Katerina Siniakova and Barbora Krejcikova claimed their maiden Grand Slam title when they beat the unseeded Japanese pair of Eri Hozumi and Makoto Ninomiya 6-3 6-3 in the French Open women's doubles final on Sunday.
Roger Federer barely broke sweat as he eased into the second round of the French Open with a 6-2, 6-4, 6-2 win against unheralded Slovakian Lukas Lacko on Sunday.
Perhaps it bodes well for men's tennis that even the French Open will be competitive this year
Say it quietly but some chinks are appearing in the suit of armour Rafael Nadal usually wears on a claycourt as the Spaniard sets his sights on a ninth French Open title.
Six different champions in the last six years suggests that tipping a French Open women's champion is something of a lottery, but those backing world No 1 Serena Williams are surely investing wisely.
Nadal will resume his fight to stay in the French Open on Thursday
World No 5 Victoria Azarenka has withdrawn from the French Open as she continues to recover from a foot injury that forced her earlier withdrawals from tournaments in Doha, Miami, Madrid and Rome.
Twice former champion Rafael Nadal will not play at this year's Wimbledon due to the wrist injury that forced the Spaniard out of the French Open, he said on Thursday.
Factbox on Spaniard Rafael Nadal, who beat Swiss Stanislas Wawrinka 6-2, 6-3, 6-1 to win his 10th French Open title on Sunday.
The 20-year-old, looking to become the first unseeded woman to lift the Suzanne Lenglen Cup since 1933, blazed her way to the final, hitting winners and errors with reckless abandon.
Only one player has beaten Rafael Nadal on his beloved claycourts this year and that man, Austria's Dominic Thiem, blocks the Spaniard's path to the French Open final.
Fourteen-time Grand Slam champion Rafael Nadal on Wednesday pulled out of the Queen's club grass-court tournament, due to wrist injury.
Australian controversial tennis star Nick Kyrgios has been slapped with the largest fine at the French Open for uttering an audible obscenity during his third round loss to Richard Gasquet.
'Right now I think that I have to find to myself again and just trying to forget the clay court season as soon as possible'
Serena Williams and Roger Federer both enjoyed Sunday afternoon strolls at Roland Garros as they seized the opportunity to gain head starts over their French Open rivals in ruthless fashion.
The Indian ace and Robby Ginepri went down to wild card entrants Rainer Schuettler and Michael Kohlmann in the Hambuirg Masters.
Titles in Barcelona, Madrid and Rome, where he dropped only three sets in the process, mean the 26-year-old is overwhelming favourite to lift the trophy for an eighth time at Roland Garros when play gets underway in Paris on Sunday.
Here is what you need to know about the prize pot on offer at Wimbledon:
Monfils was playing in his first match in nearly seven months after the season resumed following the COVID-19 hiatus.
Rafa Nadal had doubted he could seal a sixth French Open title having started in shaky form and with rivals looking imperious, but the Spaniard need not have worried after triumphing with another claycourt masterclass.
Images from day three of the 2011 French Open in Paris, on Tuesday.
A trio of tennis moms-Naomi Osaka, Angelique Kerber and Caroline Wozniacki-are poised for comebacks at the Australian Open.
It took nearly five hours of gruelling tennis for Rafael Nadal to fend off Grigor Dimitrov and book a dream Australian Open final against Roger Federer but before Melbourne Park the Spaniard endured a season of heartache and doubt.
Serena Williams overcame a gritty challenge from unseeded Dutchwoman Kiki Bertens, winning 7-6(7), 6-4, to reach the French Open final, in Paris, on Friday. She will meet Garbine Muguruza, who reached her second Grand Slam final when she beat Australia's Samantha Stosur 6-2, 6-4 in the first semi-final at Roland Garros.
Having returned empty-handed from all his four forays to the final, Borg's failure to win the US Open remained the biggest regret in what was otherwise an illustrious career.
Roger Federer's struggles continued when he was beaten 7-6 (2), 6-4 by fast-rising Austrian Dominic Thiem in the third round of the Italian Open in Rome, on Thursday.
The German pair, who beat 16-time major champions Mike and Bob Bryan en route to the final, raced through the opening set with two early breaks.
Timea Bacsinszky and Jelena Ostapenko will celebrate birthdays on Thursday, but one will be left crying into her cake as they face off in the French Open semi-finals.
All the ingredients are in place for a classic finish to the US Open women's singles tournament with a stellar cast set to take the court on Friday in semi-final action at the year's final Grand Slam.
A Roland Garros final against Rafael Nadal should have been the highlight of Spanish warrior David Ferrer's career. Instead what he got was a "strange" match featuring driving rain, invaded by "strange" people "without clothes on" and he will now "strangely" be ranked above Nadal despite finishing second best.
Rafael Nadal made light work of fellow Spaniard David Ferrer to win a protest-interrupted French Open final 6-3, 6-2, 6-3 on Sunday and become the first man to win eight singles titles at the same tournament.
French Open finalist Rafael Nadal has pulled out of next week's Wimbledon warm-up event at Halle in Germany, citing fatigue after a busy few weeks of tennis.